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KMID : 0370819920070010111
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Yonsei Journal Dental Science
1992 Volume.7 No. 1 p.111 ~ p.124
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AN EXPERIMENTAL STUDY OF THE EFFECTS OF COLLAGEN ABSORBABLE HEMOSTAT AND POROUS REPLAMINEFORM HYDROXYAPATITE ON PERIODONTAL TISSUE HEALING IN DOGS
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Abstract
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The purpose of this study was to evaluate the effects of collagen absorbable hemostat and porous replamineform hydroxyapatite in treatment of periodontitis of dogs.
Experimental periodontitis was induced by the ligation of orthodontic elastic threads in the premolars and 1st molar of 5 adult dogs for 10 weeks.
After 10 weeks, regenerative procedures were performed in experimental areas divided into 3 groups.
@ES The three groups were as follows :
@EN 1) flap operation(control group)
2) flap operation with collagen absorbable hemostat(experimental group I)
3) flap operation with collagen absorbable hemostat and porous repamineform hydroxyapatite(experimental group II)
At the 1st day, 1, 3, 12 and 26th week, dogs were serially sacrificed and specimens were prepared with hematoxylin-eosin stain for the light microscopic evaluation.
@ES The results were as follows :
@EN 1. The resorption of collagen absorbable hemostat started from the 1st day. At the 3rd week, it remained a little in experimental groups.
2. In control group, epithelial migration was started at the 1st week, at the 12th week was observed at the apical portion of the notch. In the experimental groups, the migration was started at the 1st week, but the junctional epithelium did not
reach
to the nothc at any time.
3. In the aspects of the inflammatory cell infiltration, it was observed severe aggregation at the 1st week, but it was reduced from the 3rd week slightly in all groups.
4. The new comentum formation was not seen in the control group. In experimental groups, the thin layer of new cementum was seen at the 3rd week on the apical portion of the notch, and new cementum was observed at the level to the coronal
portion
of
the notch at the 12th week.
5. the new bone formation was not observed in the control group. in the experimental group I, new bone fromation was seen at the 26th week. But in experimental group II. It was formed from the 3rd week around the implanted material near the
alveolar
bone and increased with time.
6. In the control group, the new connection of collagen fiber and the root surface was not seen. In the experimental groups, collagen fiber was parallely arranged from the 3rd week, and functional arrangement was seen at the 12th week.
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KEYWORD
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